People Principal Investigator Pekka Taimen, MD, PhD I am a Professor of Molecular Pathology at the University of Turku and a part-time Chief pathologist at Turku University Hospital. I have more than 20 years of experience in cell biological and translational research and 15 years of experience in clinical pathology. After obtaining my PhD at the University of Turku in 2005, I did my postdoctoral studies in the laboratory of Professor Robert D. Goldman at Northwestern University (Chicago, USA) in 2008-2009 and started my own group at the Institute of Biomedicine, University of Turku in 2011. I worked as the Academy of Finland Clinical Researcher in 2015-2019 and I hold a title of docent in clinical pathology as well as in molecular pathology. In the clinical pathology work, my main focus is on genitourinary pathology (prostate, bladder) and cardiovascular pathology. Senior Researchers Gun West, MSc, PhD Postdoctoral researcher working on signaling pathways involved in the development of laminopathies. I obtained my Master’s degree in biochemistry from Åbo Akademi University in 2005 and thereafter did my PhD focusing on proteins’ structural binding properties in Peter Mattjus’ Lab at Åbo Akademi University. I joined Taimen lab already at the early beginning in 2011 and I have been involved in several research projects over the years. In my current research project, I study unfolded protein response and ER stress related mechanism involved in the pathogenesis of diseases caused by lamin A/C mutations. Vanina Dahlström-Heuser, PhD Doctoral Candidates Kimmo Kettunen, MD I received my MD degree from University of Turku in 2020. I joined the Taimen lab already during my medical studies and currently hold a PhD student position supported by the Turku Doctoral Programme of Molecular Medicine (TuDMM). My main interest is in the pathogenesis and patient-derived cell culture models of bladder cancer. Using these methods we aim to develop novel tools to improve the stratification of bladder cancer patients. Irena Saarinen, MD I obtained my MD degree from the University of Oulu in 2021 and currently I am doing my residency in internal medicine. Besides clinical work, I am finishing my PhD, which focuses on immunohistochemical and genetic signature of primary prostate cancer and how these tumor characteristics affect tumor detection by MRI and 18F-fluciclovine- and PSMA-PET imaging. We are especially interested in understanding 18F-fluciclovine transport and accumulation, as well as the heterogeneity of prostate specific membrane antigen (PSMA) expression within prostatic tumors of different Gleason grades and genotypes (e.g., PTEN loss, TMPRSS2-ERG fusion). We hope that these studies will further improve imaging-based classification of prostate cancers and patient stratification for different treatment options. Eva-Maria Talvitie, MD I received a MSc degree in Biomedicine in 2007 and MD degree in 2013, both from University of Turku. Thereafter I did my training in pathology at Turku University Hospital in 2014-2020 and I received a specialist’s degree in 2020. My PhD project focuses on molecular pathology of non-small cell lung cancer. Using highly validated tissue micro arrays, FoundationOne NGS data and detailed clinical follow-up data, we study the mutational spectrum, tumor mutation burden, biomarkers, and their prognostic and predictive value in surgically resected lung cancers. Arian Askari, MSc Aino Kivikallio, MD Oskar Haavisto, MSc Graduate Students Kaisa Saarikoski, BSc Alumni Minttu Turunen Laura Virtanen Song-Ping Li Matias Blomqvist Mona Halme Josef Gullmets Anni Keinänen